The Questionnaire Survey Method in Medicine on the Example of Treatment Adherence Scales

Aim. Development, testing and validation of the original questionnaire “Adherence Scale” (AS) in PRIORITY ANTEY observational studies (OS). Materials methods. The OS assessed adherence to statins 298 patients with high very cardiovascular risk for 3 months. oral anticoagulants 201 non-valvular atrial fibrillation 1 year. Adherence was using AS questionnaire, which external performed (with calculation Cohen's Kappa coefficient). reference methods were validated direct medical interview. And internal (consistency questions on Spearman's correlation analysis). sensitivity, specificity (ROC analysis) retest reliability scale (Cronbach's alpha) also determined. Results. In kappa method survey 0.76 (high consistency), questionnaire=0.28 (low consistency). High consistency (correlation coefficient=0.78, p<0.0001) confirms validity scale. Evaluation main characteristics modified showed between results questionnaire: kappa=0.94 AS). alpha). confirmed by a strong statistically significant test questions: coefficient=0.80, p<0.0001. sensitivity test, determined ROC analysis, 89%, 62%. Conclusion. developed tested new (modified version) – indicators reliability, sensitivity. This ensures its ease use assessing various types determining leading factors non-adherence, allows scientific clinical practice.